Graft Vs. Host Syndrome

What is graft versus host disease?

Graft versus host disease (GvHD) is a condition that might occur after an allogeneic transplant. In GvHD, the donated bone marrow or peripheral blood stem cells view the recipient’s body as foreign, and the donated cells/bone marrow attack the body.

There are two forms of GvHD:

  • Acute graft versus host disease (aGvHD).
  • Chronic graft versus host disease (cGvHD).

The Cleveland Clinic goes into much more detail here.

Where does Hyperbarics fit in with this disease?

A study in 2008 explored "Effect of hyperbaric oxygen on acute graft-versus-host disease after allogeneic bone marrow transplantation." The results showed that the survival rate in HBO group was much higher than that in allogenetic bone marrow transplantation.

It is concluded that HBO has more remarkable advantage in improving the rate of survival.

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